The role of Helicobacter Pylori in Hyperemesis Gravidarum

Tolga TUNCEL, Gültekin KÖSE, Nurettin AKA, Pınar KUMRU
İstanbul-Turkey

OBJECTIVE: The aim of this study was to investigate the role of Helicobacter Pylori in the etiology of hyperemesis gravidarum.
STUDY DESIGN: 50 pregnant women who consulted our clinic for nausea, vomiting and weight loss and diagnosed with hyperemesis gravidarum as a result of the examinations and inspections, constituted the study group and 88 pregnant women who didn't have such complaints constituted the control group. In both groups, serum Helicobacter Pylori IgG was investigated. The results were evaluated using the Fisher's Exact Test.
RESULTS: Helicobacter Pylori IgG was detected to be positive in 48 of 50 patients (96%) who were diagnosed with hyperemesis gravidarum, whereas Helicobacter Pylori IgG was detected to be seropositive in 73 of 88 patients in the control group (82.9%). The intergroup difference was found to be statistically significant.
CONCLUSIONS: Helicobacter Pylori infection plays a role in the etiology of hyperemesis gravidarum.
(Gynecol Obstet Reprod Med 2006; 12:100-102)

Key Words: Hyperemesis gravidarum, Helicobacter Pylori