Özet

Antifosfolipid sendrom (APS) tekrarlayıcı vasküler trombozlar, gebelik kaybı ve çeşitli antifosfolipid antikorların varlığı ile karakterize klinik tablodur. APS’ da trombositopeni, livedo retikülaris (LR), kalp kapak hastalığı, nefropati, hipertansiyon (HT) gibi bulgular sıklıkla birlikte bulunur. Bu makalede APS tanı kriterleri, klinik bulguları ve yenilikler gözden geçirilmiştir.
Anahtar Kelimeler: Antifosfolipid sendrom, Nefropati, Livedo retikülaris, Hipertansiyon, Trombositopeni

Antiphospholipid Syndrome

Summary

Antiphospholipid syndrome (APS) is a disorder that is characterized by recurrent vascular thrombosis, pregnancy loss and presence of several antiphospholipid antibodies. In APS, the signs such as thrombocytopenia, livedo reticularis (LR), heart valve disease, nephropathy and hypertension (HT) coexist. The APS criterias, clinical findings and newnesses were revised.
Key Words: Antiphospholipid syndrome, Nephropathy, Livedo reticularis, Hypertension, Thrombocytopenia