Mid-trimester Genetic Amniocentesis: GATA Experience
Sadettin GÜNGÖR, İskender BAŞER, Ali ERGÜN
Ankara-Turkey
OBJECTIVE: To evaluate the data about amniocenteses those were performed in our department and to compare indications, procedure related losses and pregnancy outcomes.
STUDY DESIGN: The study was carried out at the Department of Obstetrics and Gynecology, Faculty of Medicine, Gülhane Military Medical Academy retrospectively. We studied amniocenteses for chromosomal analysis between 2002 and 2004. The data of the patients were obtained from their records.
RESULTS: The mean (±SD) gestational age at amniocentesis was 17.9±1.3 weeks (range 16-22 weeks). The most common primary indications for amniocentesis were advanced maternal age (37.0%) and positive screening test result (36.5%). In 1452 of the procedures (99.7%), amniotic fluid was obtained by a single puncture. A chromosomal abnormality was detected in 47 women (3.2%) who preferred termination of pregnancy. The total fetal loss rate was 0 in 1456 (0.0%) within two weeks following amniocentesis
CONCLUSION: Amniocentesis is a safe and reliable technique with low fetal loss rates in complicated and uncomplicated pregnancies in our study group.
(Gynecol Obstet Reprod Med 2006; 12:000-000)
Key Words: Amniocenteses, Prenatal diagnosis, Outcome, Fetal loss